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yxfbbiedtj
Wysłany: Sob 11:12, 12 Mar 2011
Temat postu: hes qap bgx sba
Hot and humid environment limbs of dogs in heat acclimatization after gunshot wound in SOD, MDA content in the experimental study
There damage (mainly damage the cell membrane and mitochondria), the injury mechanism is a wide range of [3 tissue damage. oxidative stress and oxidative stress of cell level outcomes related to stress in a certain range of oxidative stress on cells are caused by a variety of injuries can be restored [5], and more than a certain limit, will cause irreversible damage to the cells. IVIDA three groups within the content of SOD and 14h after injury prompts the body prior to the performance under stress produce large amounts of oxygen free radicals, causing a large number of antioxidant enzymes SOD and other relations, two is the trade-offs between the expression of the temperature and humidity, gunshot wounds, under the conditions of thermal adaptation can not change this relationship. The results suggest that: ① group of normal temperature and humidity MDA and SOD after injury were higher Description limbs wounded body can increase lipid peroxidation. injured when the pulse of the transient cavity and the shock wave effect [6] wound track caused by the surrounding tissue microcirculation, resulting in a large number of oxygen free radicals; ② high temperature and humidity group compared with the normal temperature and humidity, MDA levels began to rise and peak time points from the 3h, 10h prior to 1h, 6h, and the peak value was significantly higher than the other two groups (P <O.05), that high temperature and high wetlands can increase the local tissue MDA, so that the body of the lipid peroxidation increased, which accelerates the body's tissues. both high temperature and humidity can significantly change the body's energy metabolism [7], makes the body increase microcirculation, ATP decreased production, and through the decomposition products and oxygen free radicals to promote cell damage through oxidation. SOD content increased high temperature and humidity set point in time prior to 1h, but the peak and the other two groups but the difference was statistically significant (P <O. 05), suggesting that high temperature and humidity can reduce the local tissue content of SOD; ③ after heat acclimatization was significantly higher SOD and lasted significantly longer, MDA were significantly decreased, with normal temperature and humidity environment, the difference was not significant, that heat acclimatization is conducive to protecting the body, improve antioxidant capacity. In short, SOD and MDA in the hot and humid environment after gunshot wound in the body limbs pathophysiology, can be used as indicators of tissue damage. SOD activity can be effective in preventing the damaging effects of oxygen, thereby reducing the stress state in the tissue damage. Thermal acclimation and the wound track after the body significantly reduced pathological changes, indicating that heat acclimatization is hot and humid environment of effective physical protection means war trauma.
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