 Wysłany: Pią 21:48, 11 Lut 2011 Temat postu: Aerobic Enantioselective Epoxidation of Styrene An |
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| Aerobic Enantioselective Epoxidation of Styrene Analogues Induced by (β-Diketone)-iron (Ⅲ) Complex
eld). m. P. 292-294 * C, +26.4 (c4.5, CC14), HNMR (CDC13, 6ppm): 5.13 (s, 3H, CH =) ,1.88-2 .21 (m, 6H, CH ), 1.43 (S, 18H, CH3) ,1.09-1_38 (m, 24H, CH2), 0.33 (d, 18H, J = 6Hz, CH3), -1.18 (s, 18H, CH3), -1.57 (s, 18H, CH3), IR1) (KBr, cm): 1545.5 (C = 0), 1501.7 (C = C); Ana1. CalcdforC63Hlo5O6Fe: C, 74.59; H, 10.43. Found: C. 74.51: H. 10.38. Generalprocedureforasymmetricepoxidation: Amixtureofstyreneanaloguef3.0mmo1), Fe (dcm) 3 (0.06mmol, 2.0mol%) ,2-ethylbutyraldehyde (9.0mmo1) in1 ,2-dichloroethane (10mLwasstirredunderatmosphericpressureofoxygenat30 ℃ for10h.T. HereactionmixturewaswashedwithsaturatedaqueousNaHCOsolution.andafterdryingoveranhydroussodiumsulfate.solventwasremovedfnvacuo.PurificationoftheresiduebyCOlumnsilicagelchromatographyaffordedthechiralstyreneanalogueOXide . AcknowledgmentThisworkissupportedbytheNationalNaturalScienceFoundationofChinaandtheDepartmentofEducationExcellentTeachersFoundation.Referencesa) T. Katsuki, K. B. Sharpless, Am. Chem. Soc. , 1980. D2, 5974. b) Y. Gao, R. M. Hmason, J. M. Klunder, S. Y. Ko, H. Masamune, K. B. Sharpless, bid. , 1987,109,5765. W. Zhang, J. L. Leobach, S. R. Wilson, E. N. Jacobsen, Am. Chem. Soc. , 199O, 112,2801. R. Irie, K. Noda,UGG España, Y. Ito, N. Matsumoto, T. Katsuki, TetrahedronLett. , 1990,31,7345. a) S. 0. Malley, T. Kodadek, Am. Chem. Soc. , 1989,111,ugg boots italia,9 l16. b) J. T. Groves, P. Viski, 0rg. Chem. , 1990,55,3628. K. A. Jorgensen. Chem. Rev. 198989431. Y. XU, Z. Y. Wang, T. P. You, Chin. Chem. Lett. , 1998. 9,607. O. F. Cheng, X. Y. Xu, W. X. Ma, T. P. YOU,. em. Lett. , 2005,6 '331. O. F. Cheng, C. S. Jiang, C. Jiang,ugg italia, S. F. Li, T. P. YOU, Canada. D. em. , 2002,22,265. Q. F. Cheng, X. Y. Xu, J. Gao, T. P. You,belstaff milano, f. D. em. , Delete, 2,tory burch shoes,1038. Received21March, 2005123456789 |
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