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PostWysłany: Nie 8:01, 20 Mar 2011    Temat postu: P34^cdc2激酶与细&

P34^cdc2激酶与细胞周期
l1,1901,66101UReves1.1JhospheryladonoftheDN、):i1Mngdeomaidof1lo1lhjstoIjcbigh/1)o叫jtyCrOftPproteiobycdc2khl:tSr。atlctiollofbndhlgaffln“y.1’ro:Nnt】、cadSciUSA,l99J.88:1a¨l12AlanSM,MarkHW,GraigME。h)ijy1ajolofcdldsmo11bycdc2kii1asJBC,199l,260:667813】]ooherR。Fheflss011yeaSccdc2/cd1_1/sI1clprotchtkinascrcguiatoofcatalytlca“vitYandnttclea.rloca1jz1tlon.Cell1989,58:,i8514LIIndgFcrlK,MikI.Wc1I。(:00pcrdionhitheinhibftorYtyrosirtcPhosPhorYIatjotlofcdc2.Cel】,t991.6{』1Ill5GautierJ.Solomo//MJ.13ooberRN,etn1.cdc25isaspecif~ctyrosiH。phosphatas0thatdireafIYactivatesP34edc2。Celi,l90l,6719716OnkuraH,KinosnltaN.MiyataniS.Thefiss[onyeastdis2+gclierequiredforchrolnosomedisjoiningencodesoil0oftweputarigetypelproteinPhosPhat[ise。CeU。990,63:99917WarbickE,GloverD.AdrosophilamelanogasterhomologoftheTIS11familyofimmediateearlygenesthatCallrcscueaedr1cdc25mutantStrai1offssj0nYeast.Gone。1994,1j124318ParkerLL.AtherionesslcrS,fecMS,ctaI.CyclinpromotesthctyrosinePhosphorylatlonofP34cde2inawed—dependentmanner。EMBOJ,1991,]0:125519LorcaT,PesquctD,ZilldyF,etal。:~k12okadalcacla—sensltlvcphosDhata—senegativelYcontrolsthccyclindegradatlonpathwaYinamphiblaneggs.Mo1Col1Bio1.199],11:117120ChangF,HerskowiLzI.IdentlficationofagonenecessarYforcc11cvc】earrestbyanegativogrowthfactorofYeast:FAR1isaninh{bltorofaG1cyclin,CLN2.eell,1990。B3:99l21HuL,AizawaS,TokuhfsaT.p53CelltroisproliferatlonofearlyBlineagecclIsbyap21(wAF1/CIP1)一indepeodentpathwaY.BlochemBio—phYsResCoramun,1995,206:948(收稿:1995—05—17修日:1995一O6—02)(本文编辑:茬舂开)
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