ncycgdxhl
ORANGE EKSTRAKLASA
Dołączył: 13 Gru 2010
Posty: 502
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Skąd: England
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 Wysłany: Sob 22:53, 26 Lut 2011 |
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,[link widoczny dla zalogowanych]
Nobel Prize in Chemistry in 2003 - from October 8,[link widoczny dla zalogowanych], 2003 data released
stodisposeof. Initswindings (termedglomemli), whichfunctionasasieve, water, ionsandothersmallmoleculesleavethebloodas'primary'urine. Over24hours, about170litresofprimaryurineisproduced. Mostofthisisre · absorbedwithaseriesofcunningmechanismsSOthatfinallyaboutonelitreofurineadayleavesthebody. Fromtheglomemli,[link widoczny dla zalogowanych], primaryurineispassedonthmughawindingtubewhereabout70% ofthewaterisreabsorbedtothebloodbytheaquaporinAQP1. Attheendofthetube, another10% ofwaterisreabsorbedwithasimilaraquaporin, AQP2. A-partfromthis,[link widoczny dla zalogowanych], sodium, potassiumandchlorideionsarealsoreab. SOrbedintotheblood. Antidiuretichormone (vasopressin) stimu. 1aresthetransportofAQP2tocellmembranesinthetubewallsandhenceincreasesthewaterresorptionfromtheurine. Peoplewithadeficiencyofthishormonemightbeaffectedbythedis-easediabetesinsipiduswithadaffyurineoutputof10 a l5litres. (Tobecontinued) CytoprotectiveRoleofCa2 a ActivatedKChannelsintheCardiacInnerMitOchOndrialMembraneIonchannelsorthemitochondrialinnermembraneinfluencecellfunctioninspecificwaysthatCanbedetrimentalorbenefi-cialtocellsurviva1. Atleastonetypeofpotassium (K) chan · nel, themitochondrialadenosinetriphosphate-sensitiveKchannel (mitoKTP),[link widoczny dla zalogowanych], isanimportanteffectorofprotectionagainstnecroticandapoptoticcellinjuryafterischemia. Hereanotherchannelwithpropertiessimilartothesurfacemembranecalciu-mactivacedKchannelwasfoundonthemitochondrialinnermembrane (mitoKca) ofguineapigventricularcells. MitoKcsignificantlycontributedtomitochondrialKuptakeofthemy-ocyte, andanopenerofmitoKcaprotectedheartsagainstinfatc-tion
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