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ORANGE EKSTRAKLASA
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 Wysłany: Czw 16:38, 03 Mar 2011 |
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Graves病患者外周血活性T淋巴细胞亚群研究
：86．0．JohnYC,[link widoczny dla zalogowanych]，eta1．Activatefl(1a)Tlymph~ytesandtheirsubsetsinautoimm…thyrokldise~*：Analysisbylaserflowmicrofluoreeytometer．JclinEndoerinolMetab，1986，62|403．7-NaofumiI·eta1．R*duetJonmthesuppresorindUCCTToeI1subsetandincre~einthehelperTcel1subsetinthyroidt~suefrompatientswithGraves’d~ease-JclieEndocrinolMetab，1987,[link widoczny dla zalogowanych]，95I17．8．BottazzoGF—eta1．Roleofabe~antHLADR*xpressinnandant远e“presentationininductionofend~rineautoimmunity．Lariat．1983／I；1115．9．PaweleeG·eta1．Expr~sionofMHcclosslepitopes0nhumanTLymphoeyteclonesCellimmuna1．1990t127520．(收稿：1993-0323修回：l993—06一O9)DETERMINAT10N0FACT1VATEDT—LYMPH0CYTESUB缸TS0FPERIPHERALBL0oDINTHEPATIEMSWITHGRAVES’DIgEASEDaiWen-juanetal(Re--re&C~ter町B，fwire，r“／vatu-坩曲．W“)ttedoublelabellingte曲niquewasappliedtodeterminetheactivatedperLpheralTlymphocytesubsetswhichexpressesconcurrentlyDRantisenandCDantisenin22patientswithGraves’diseaseand20healthycontrols．ThedecreaseofpercentageofcDandtheincreaseofcD／CDs+ratiocellsaswellasvarioustheelevatedpercentageofDRTlymphocytes，especLallytheDRCDtcellwerediscoveredinthepatientswithGraves,[link widoczny dla zalogowanych]，diseasv．TheabnormalityofequallibriumofactivatedTlymphocytesubsetsandasignificantincreaseofDRCD4+／DRcDratioweredetectedinactiveperiod．Incompar~onwiththeactivephasetheDRcDandDRcDcellsdecreasedinremissionaftertreatment，butDRCD,[link widoczny dla zalogowanych]；cellsremainedunchanged．ThedecreaseintheratioofCD~／CD=+cellswaslessmarkedthanthatofDRcD／DRcDcells，whichfellintothenormalrange．Thisinvest'崤ationsuggeststhatanexcessiveactivationofThelpercellsaswellasadeficien
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