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asbryobvrz · Wysłany: Wto 20:36, 08 Mar 2011

Lipoprotein glomerulopathy in 1 case and review of literature

, Granular degeneration,[link widoczny dla zalogowanych], individual 'tubular cavity see lipoprotein r] management,[link widoczny dla zalogowanych], the quality of renal 『at small focal Bian J fibrosis. Mild renal artery wall thickening. (2) Immunofluorescence: Frederick r see six glomeruli, lgA (+), Ig (;(+/ a), IgM (++), C3 (+),(,[link widoczny dla zalogowanych], lq 【+ +), FI ( + +),[link widoczny dla zalogowanych], immunofluorescence linear points along the capillary loops; lnA (++), Atx) B (+++). (+++), Vascular loop cavity contents were 『c = {Gang massive autumn, (3) electric microscopy Apricot: review see four glomeruli, glomerular capillary m ① J Seoul Provincial Hospital (f Seoul bamboo II1 Medical Sciences) Epilepsy Branch (』State 510120) ② leaves a hospital in Guangdong Province (Canton Province Seoul Medical Branch: Home) Pediatric (Guangzhou 510120, China) lumen expansion bolt m filled with lipid-like protein, diffuse epithelial cell foot processes fusion. No special quality tubular renal disease. (4) pathological diagnosis: lipoprotein 'ffd,[link widoczny dla zalogowanych], ball disease. Discuss the very low incidence of LPG, l989 _ 【years (j other first reported and named the disease, since the umbrella world (English literature) l1 a report of 65 cases only. China's domestic I2 by the Chen Huiping, etc. In 1997 the first report in l {1 paper towel literature database, we retrieved 59 cases were reported, the largest number of reported cases of l6 cases: Ll (j were focused on the Island race. the door wide race French only 2 cases reported _l. LI】 G age from 4 years to 69 years, ranging on average (32.74-l6.5) years old, male and female patients account for nearly 2: l. The majority of patients are sporadic, only a small number of patients with familial disease. A few patients associated with lgA nephropathy, membranous nephropathy, lupus nephritis, or psoriasis. LPG to a large number of eggs were usually from the urine as the clinical manifestations, most patients with nephrotic syndrome diagnostic criteria to Ke more than 2 / 3 of the patients with microscopic hematuria, 1 / 2 to patients with impaired renal function slowly progressive IP (Xi rare risk of hyperlipidemia and other manifestations of systemic damage to be about l / 2 of the patients had symptoms of low n and high protein m canthal pressure, more than 2 / 3 patients with a parallel decline in renal function Lj anemia I1 .. 【ffL plasma apolipoprotein E (ApoE) in patients with elevated total LPC-foot characteristic performance, increased range of 2 to 3 times, but Zhang The study found that patients in China and other less than l / 3 of the patients (5 / 16) increase of more than 2 times. ApoE LDL receptor caused by mutations in connection dysfunction may be caused u, G major of the original storm onset, LPG to lipoprotein thrombi in the lumen to allow full pathological features of oil red O staining, ApoB and AI) () E immunofluorescence staining and electron microscopy and dry fine vacuolization bolt f layering confirm the nature of lipid protein. The renal biopsy cases with typical pathological features of LPG. II, (the lack of effective treatment, usually mow corticosteroids, immunosuppressants, anti-coagulation therapy, plasma exchange and lI) I apheresis treatment such as invalid, and in the kidney recurrence after transplantation. but including fibrate (fibr ~ tes), including lipid-lowering drug therapy can make some of the clinical symptoms and pathological changes have been alleviated 1 ..