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asbryobvrz · Wysłany: Pon 21:02, 07 Mar 2011

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Different Helicobacter pylori infection and gastric mucosal lesion Correlation between the expression of cyclooxygenase

Difference compared with the CSG expression was significantly (P 0.05); CSG and GC in the case of Hp-positive and negative expression of COX-2 was no significant difference (P> 0.05); but in the CAG,[link widoczny dla zalogowanych], IM,[link widoczny dla zalogowanych], DYS Hp-positive cases in the COX-2 expression was significantly higher than that of Hp-negative patients (P 0.05). However,[link widoczny dla zalogowanych], CAG,[link widoczny dla zalogowanych], IM and DYS in the gastric mucosa in Hp-positive cases of COX-2 expression was significantly higher than that of np-negative cases (P <0.01), suggest np infection induces the expression of COX-2 formation in the early stages of gastric cancer. CAG, IM and DYS are precancerous lesions of gastric cancer, gastric cancer is closely related with this study, COX-2 in precancerous lesions and GC expression was significantly higher than that of CSG, prompted the expression of cox-2 may be developed to CSG GC molecular markers, COX-2 expression in seven adjustment may be an early event during GC one place. COX-I in different gastric lesions was no significant difference, Hp infection on the expression of COX-l had no significant effect, improving c0x-l as a stable enzyme exists in different gastric mucosa lesions, prompting physiological PG synthesis, since to protect the gastric mucosa, maintenance of environmental stability and regulation of the body cell physiological activities.