Dołączył: 22 Kwi 2011
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|Wysłany: Czw 9:49, 26 Maj 2011
Picking up the story the Sanger Institute says, To create the rate of evolution, the group surveyed an district of the Y chromosome. The Y chromosome is matchless in that, apart from infrequent mutations, it is passed unchanged from dad to son; so mutations amass slowly over the generations.
The BBC quotes Joseph Nadeau, from the Case Western Reserve University in the United States as mentioning, We are eventually obtaining nice authentic estimates of genetic features that are urgently needed to comprehend who we are genetically.
Jack Haldane, along with Ronald Fisher and Sewall Wright founded the learn of population genetics; this namely the science of how such entities for genetic mutations, natural selection, and genetic drift bring about evolutionary alteration.
Most of these mutations are quite harmless and occasion not ill effects to humans health alternatively physical appearance.
Sequencing Technology Confirms Haldane’s Estimate
Understanding the rate at which mutations happen could lead to ways in which the negate effects of such accidents might be diluted.
After many generations, the researchers found there were merely a dozen variations, and that only four were true mutations that had occurred surely through the generations.
Now an international group of 16 scientists says Haldane was right. One of the scientists is Dr. Yali Xue from the Wellcome Trust Sanger Institute in Cambridgeshire, England. A newspaper release from that union (August 27, 2009) points out that through the go of Xue and colleagues, Remarkably, the new research, published today in Current Biology, shows that these early estimates were spot on in total, we entire carry 100 200 new mutations in our DNA. This is equivalent to an mutation in each 15 to 30 million nucleotides.
The BBC notes that It is wished that the discoveries may lead to new ways to reduce mutations and provide insights into human mutation.
Writing for BBC News (September 2, 2009) Sudeep Chand reports that the scientists saw at thousands of genes in the Y chromosomes of 2 Chinese men. They knew the men were distantly related, having shared a mutual ancestor who was nativity in 1805.
According to recent studies, each person has 100 current mutations in their DNA. Almost 70 years ago the father of modern genetics Haldane speculated that this might be so.
Chromosomes of Chinese Men Studied
The Genome 10K Project
The Four Steps of Evolution
What Is a Genetic DNA Mutation?
Science Daily reports (September 1, 2009) that Understanding mutation rates is opener to many appearances of human evolution and medical research: mutation is the final source of all our genetic variation and provides a molecular clock for measuring evolutionary timescales. Mutations can also lead instantly to diseases like cancer.
Medical Research Aided at Understanding Genetic Mutations
In 1935 [link widoczny dla zalogowanych], Haldane studied a group of men in London with hemophilia. Through this research he came apt the conclusion that every person had about 150 genetic mutations.
Haldane Pioneered Population Genetics
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