荷转移分光

lin06900 · Wysłany: Pią 19:55, 18 Mar 2011

荷转移分光光度法测定注射用阿昔洛韦的含量
痛等均有不同程度的改善，优于平消胶囊组。结论：(1)该胶囊制剂在常温条件下存放质量稳定。(2)消瘤Ⅱ号可有效控制淋巴结转移灶的发展，并可提高患者的生活质量，缓解临床症状，有效延长肿瘤患者的生存期，对机体无不良反应，值得进一步研究。[关键词]消瘤Ⅱ号胶囊；研制；质量标准；淋巴结转移；临床疗效[中图分类号]R285．65[文献标识码]A[文章编号]…)1―5213(2006)07―0802―03DevelopmentandtherapeuticeffectofXiaoliuIIcapsuleonthecervicallymphnodemetastasisWUHong-bin，LIXiao―ping，XUMei―ying，LUGuo―chun(CancerHospitalofFudanUniversity，Shanghai，200032，China)ABSTRACT：OBJECTIVETodevelopXiaoliuIIcapsule，analyzeitsqualityandstudyitstherapeuticeffectoncervicallymphnodemetastasis．METHODS(1)Scorpio、BulbusFritillariaeThunbergii、SemenLitchiweremixedtogetherintheratioof1：1：1andthenpreparedintheforillofcapsulesafterdrying，grinding，sterlingandgriddling．ThespecificationwasestablishedaccordingtotherequirementofChinesepharmacopoeia(2000)．(2)100patientswithcervicallymphnodemetastasisweredi―videdinto2groupsaccordingtotheprincipleofrandomlycontrolledtrials：experimentalgroupwhichwasgivenXiaoliuIIcap―sHiesandcontrolgroupwhichwasgivenPinxiaocapsule．TheefficacyofprimarysiteandcervicallymphnodemetastasiswereevaluatedonthebasisoftheWH0criteria．Thephysicalstatus、clinicalsymptoms、painrelievementandweightchangesofthepatientswerealsoevaluated．SurvivalratewascalculatedwithKaplanMeiermethod，andCoxregressionanalysiswasper―formedtoidentifyadverseprognosticfactors．RESULTS(1)XiaoliuIIcapsuleswerestableforatleast1yearat5～3()℃．(2)In50assessablepatients，noneachievedCR，6achievedPR，44hadSD，andnonehadPD；whilein50contro1patients。[作者简介]吴洪斌，男，学士，副主任药师，电话：021―64175590―3542，E―mail：wuhongbin3327@126．COrn
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