State Pavilion and omeprazole on patients with upp

ncycgdxhl · Wysłany: Pon 22:25, 21 Mar 2011

State Pavilion and omeprazole treatment combined with observation of upper gastrointestinal bleeding

, Fecal occult blood became negative; (2) endoscopy: bleeding stopped, bleeding ulcers no fresh signs; (3) clear tube leads to fluid, non-coffee-like liquid. Any of the above three is regarded as an established bleeding stopped, otherwise regarded as invalid. Markedly: 48h medication to stop bleeding; effective: 48 ~ 72h medication to stop bleeding; invalid: there is still bleeding after 72h treatment. Statistical analysis of the total effective rate of 1.4 () I (+ markedly effective cases the number of cases) / observed number of cases × 100, t-test measurement data, count data with the Y test. 2 results of clinical efficacy of 2.1 in Table 1. Table 1 treatment group and control group, treatment effect ()] Note: The two groups Q inspected: Y-5.9979, P 0.05). By observation or use of antagonistic drugs, responses are reduced to disappear. Before and after treatment of blood, urine and liver and kidney function revealed no obvious abnormalities. 3 Discussion of upper gastrointestinal bleeding is common in acute gastrointestinal diseases, one of the reasons cause more bleeding, the most common peptic ulcer. If the treatment is often not in time lead to serious consequences, and even endanger the lives of patients L】]. High acid state is unfavorable factors for upper gastrointestinal bleeding, one bleeding body fluids and the role of platelets induced only in the pH> 6.0 can play a role when, in the case of a small amount of acid, platelet aggregation and clot formation on will be inhibited. Acid-suppressing medications to provide a conducive environment to stop bleeding, is not directly involved in hemostasis, thus inhibiting gastric acid secretion and the application of hemostatic drugs to treat upper gastrointestinal bleeding in one of the main measures. In recent years, started as a drug of first choice hemocoagulase ulcerative disease, it has a fast, precise hemostasis [2]. State Pavilion for the venom of its active ingredients and the phospholipid-dependent thrombin clotting factor X activating enzyme (roar), is a targeted biological hemostatic agent. The hemostatic mechanism of action different from other similar drugs, venom thrombin clotting process directly on the Stage 3, the fibrinogen into fibrin and accelerate the blood coagulation; roar role in the clotting process, stage 1,[link widoczny dla zalogowanych], promoting factor X changes to X, and can also promote platelet aggregation and irreversible release reaction, accelerated blood clotting and promote bleeding vascular endothelial cell growth, so that wound healing. Losec is a research and development in recent years, the mechanism is different from the Hz receptor antagonist effect of the new anti-ulcer drugs. It specifically acts on gastric parietal cells, reducing cell wall HI (previous TP activity, so that hydrogen ions within the parietal cells can not be transferred to the stomach cavity and reduce stomach acidity,[link widoczny dla zalogowanych], gastric acidity so close to neutral to ensure the formation of clots within blood vessels or blood clot is not digested, to avoid bleeding L3]. Losec as proton pump inhibitors, which block the H was excreted to the parietal cells in vitro, almost completely inhibit gastric acid secretion, and lasting effect. Therefore, the state pavilion of Losec and hemostatic agent combined application of hemostatic agents can play a better role,[link widoczny dla zalogowanych], and ultimately achieve hemostasis and prevent rebleeding purposes. The results indicated that application of the state not only played a hemostasis Pavilion, at the same time Application of the proton pump inhibitors increase gastric pH, creating a favorable environment to stop bleeding, so that the total effective rate of 95.9 bleeding, said Mingbang kiosks and omeprazole on patients with upper gastrointestinal bleeding,[link widoczny dla zalogowanych], efficacy was significantly better than omeprazole group, hemostasis rapidly, accurate, and practical convenience,[link widoczny dla zalogowanych], side effects, is an ideal clinical hemostatic drugs.